A breakthrough in understanding how a single-cell parasite makes ergosterol (its version of cholesterol) could lead to more ...

A breakthrough in understanding how a single-cell parasite makes ergosterol (its version of cholesterol) could lead to more effective drugs for human leishmaniasis, a parasitic disease that afflicts ...

A breakthrough in understanding how a single-cell parasite makes ergosterol (its version of cholesterol) could lead to more ...

"This means that isolates that are already resistant to our first line treatments could develop resistance to new drugs 5 ...

Fungal genomics is a scientific discipline that concerns the genome, encompassing the entire hereditary information, of fungi. Fungal genomics can, for example, be used to study fungal evolution ...

Perform susceptibility testing as an adjunctive to treatment for patients with disease and long-term azole treatment and/or recurrent cultivation of an Aspergillus spp. Perform susceptibility ...

fumigatus has important implications for the scope of clinical antifungal stewardship. Given the human health consequences of disease caused by azole-resistant Aspergillus, it is hardly surprising ...

College of Life Sciences, Institute of Life Science and Green Development, Hebei University, Baoding 071002, China Hebei Innovation Center for Bioengineering and Biotechnology, Hebei University, ...

suggesting the potential for enhanced patient outcomes and significantly improving prophylactic strategies against fungal PJIs in joint replacement surgeries by preventing and treating fungal ...

Azoles are also used as antifungals for treating clinical and agricultural fungal pathogens. The triazole class of fungicides are demethylase inhibitors that inhibit lanosterol 14 alpha-demethylases ...

There was high-quality evidence that oral azole and terbinafine treatments were more effective for achieving mycological ... Cochrane Systematic Review Kreijkamp-Kaspers S et al. Oral antifungal ...