Background: Preeclampsia (PE) is a pregnancy complication characterized by hypertension, proteinuria, endothelial dysfunction, and complement dysregulation. Placenta-derived extracellular vesicles ...

In ectopic gestations, it prevents the proliferation of the cytotrophoblasts. This results in decreased trophoblast ß-hCG production, which causes decreased secretion of progesterone by the ...

Reproductive success hinges on the presence of a robust and functional placenta. Examining the placenta provides insight about the progression of pregnancy and valuable information about the normal ...

The other pathway that these cells can take when differentiating is one that forms the extravillous cytotrophoblasts. The specialized epithelium of the syncytiotrophoblast has a number of ...

A previous report has shown that HCMV infection inhibits the proliferation and invasion of extravillous cytotrophoblasts (EVT) through mRNA downregulation of core Hippo pathway components, including ...