Human cells contain two types of adenosine deaminases (ADA) each with unique properties: ADA1, which is present in all cells ...

在动荡的生物世界里，病毒的威胁无处不在，无论是细菌还是人类，生命过程中都需要面对这一挑战。而令人惊讶的是，细菌也是具有独立自我保护能力的小生物，拥有自己的"免疫系统"来抵御病毒的侵袭。近日，中国药科大学药学院、重庆中国药科大学创新研究院的科研团队在《 ...

2024年12月13日，中国药科大学肖易倍教授、陈美容副教授、陆美玲副教授为共同通讯作者合作在Science杂志上以“First Release”形式在线发表了题为Antiviral signaling of a type III ...

During parasitoid wasp infection, activated immune cells of Drosophila melanogaster larvae release adenosine to conserve nutrients for immune response. S-adenosylmethionine (SAM) is a methyl group ...

细菌虽然比人类简单，却也有自己的“免疫系统”用来保护自己免受噬菌体感染。这些细菌免疫系统非常多样化且复杂，它们的工作原理至今仍在被科学家探索。研究细菌的这些“免疫系统”不仅有助于揭开生命活动的奥秘，还直接推动了科学技术的进步，比如以CRISPR-Ca ...

ProQR Therapeutics NV. (Nasdaq: PRQR) (ProQR), a company dedicated to changing lives through transformative RNA therapies based on its proprietary Axiomer™ RNA editing technology platform, today ...

2,3,6 Several oocyte-specific proteins have been categorized as crucial to forming cytoplasmic lattices, particularly PADI6 (peptidylarginine deaminase) and the SCMC (subcortical maternal complex).

研究团队通过生物信息学分析发现，某些III型CRISPR-Cas系统缺少传统的核酸切割功能，但却携带一种脱氨酶（CAAD）和一种核苷酸水解酶（Nudix）。这种独特的组合让科学家推测，这类系统的免疫机制可能与能量代谢密切相关。

This three-step pathway involves the enzymes carboxylesterase, cytidine deaminase and thymidine phosphorylase (Figure 1), all of which are expressed in hepatic and tumor tissue. In particular the ...

研究由肖易倍教授、陈美容副教授和陆美玲副教授主导，论文题为《Antiviral signaling of a type III CRISPR-associated deaminase》。研究团队的核心发现是CRISPR ...