The Prolyl Endopeptidase FAP pipeline drugs market research report outlays comprehensive information on the Prolyl Endopeptidase FAP targeted therapeutics, complete with analysis by indications, stage ...

These new therapeutic options -- endothelin antagonists, dual angio- tensin-converting enzyme-endopeptidase or vasopeptide inhibitors, and recombinant preparations of human brain natriuretic ...

These agents are essentially "super ACE inhibitors," and have a dual action, combining inhibition of both the angiotensin-converting enzyme (ACE) and neutral endopeptidase. The latter enzyme is ...

NSD-2 is crucial for AR activity in prostate cancer, promoting tumor growth and offering a potential therapeutic target for advanced prostate cancer treatment.

Macrophages are important cellular reservoirs of chikungunya virus (CHIKV), but the viral and host determinants that ...

Dendritic cells (DCs) are heterogeneous. The migratory DCs traffic from tissues to lymph nodes, where they mature. The resident DCs spend their entire lifespan in the lymphoid organs in an ...

内肽酶（endopeptidase）又称内切蛋白酶（endoproteinase），是蛋白水解肽酶，可催化多肽链中非末端（即分子内）肽键的水解，正好与外肽酶相反（可催化末端肽键的水解） [1] 。因此，内肽酶不能将肽分解成单体，而外肽酶可以将蛋白质分解成单体。内肽酶的一个 ...

24 Gastroenterology and Liver Unit, Royal Hallamshire Hospital & University of Sheffield, Sheffield, UK Correspondence to David S Sanders, Gastroenterology and Liver Unit, Royal Hallamshire Hospital & ...

Objective The short isoform of thymic stromal lymphopoietin (TSLP), a cytokine constitutively expressed by epithelial cells, is crucial in preserving immune tolerance in the gut. TSLP deficiency has ...

Vascular endothelial cells, serving as a barrier between blood and the arterial wall, play a crucial role in the early stages of the development of atherosclerosis, cardiovascular diseases (CVDs), and ...