Glycans play an important role in modulating the interactions between natural killer cells and antibodies to fight pathogens and harmful cells.

Researchers have identified a new complex-carbohydrate biomolecule, or glycan, that plays a key role in the nasal colonization of the Bordetella bacteria responsible for whooping cough. The discovery ...

All N-glycan cores in eukaryotes contain two conserved GlcNAc residues at the protein attachment site, so they are good candidates for replacement in a general labeling approach. In addition ...

Several glycan-masked mutants showed significantly decreased antibody binding to non-CD4bs “off-target” epitopes while maintaining strong binding to CD4bs-specific bnAbs. Furthermore ...

研究人员发现了宿主防御金黄色葡萄球菌的一个关键免疫因子，为以前疫苗策略的失败提供了一个潜在的解释。研究表明，健康人产生针对金黄色葡萄球菌表面糖的IgM和IgG抗体，并发现IgM抗体在杀死细菌方面比IgG抗体更有效。金黄色葡萄球菌菌血症患者IgM抗体水平低与疾病死亡率和细胞杀伤受损相关。

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Scientists have found a way to create artificial sugars that could lead to better ways to diagnose and treat diseases more ...

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Wheeler Bio, Inc., an agile contract development and manufacturing organization (CDMO), announced today an expansion in ...

Skin-secreted adhesives, or glues, are highly effective defense adaptations that have evolved recurrently in a small number ...

ATUM and Wheeler Bio embrace a forward-thinking approach to biologics development, one that transcends conventional ...