Trials evaluating the use of hypertonic saline solutions for resuscitation after traumatic injury have not shown an overall mortality benefit compared with isotonic fluid administration.
Hypertonic saline refers to any saline solution with a concentration of sodium chloride (NaCl) higher than physiologic (0.9%). Commonly used preparations include 2%, 3%, 5%, 7%, and 23% NaCl.
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Hypertonic saline nose drops reduce the duration of symptoms associated with viral upper respiratory tract infections in children.
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