Many receptor interactions are scarcely characterized, including loricrin, desmoglein-1, desmocollin-1 and keratinocyte lipids. Loricrin comprises up to 80% of protein on terminally differentiated ...
Sneha Khedkar is an Assistant Editor at The Scientist. She has a Master's degree in biochemistry and has written for Scientific American, New Scientist, and Knowable Magazine, among others. View full ...
Single-cell RNA sequencing reveals mechanoresponsive fibroblasts as a key driver of keloid aggressiveness, with endothelial cell and keratinocyte transitions also involved, paving the way for ...
Adult clinical trials found that Tremfya could treat plaque psoriasis by 16 weeks. Follow-up analysis found that roughly 23% of patients remained plaque free for more than 156 weeks. The Latest ...
The final strategy involves inactivation of secreted effector cytokines. Tumour necrosis factor α (TNFα) appears to be a critical cytokine for many of the clinical features of psoriasis, including ...