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生理动力学模型及其在健康风险评估中的应用进展和展望
另一类应用则是从PODin vivo出发,利用反向剂量法(reversed dosimetry)推导与其对应的PODin vivo,用于指导最大安全暴露剂量的制定。目前更多的研究工作聚焦在有效的、可用于风险评估的体外生物活性的信息方法开发(如多能干细胞、3-D细胞培养和组织芯片等),以及 ...
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