Although much less is known about mRNA export, a fundamentally different mechanism may be at work. This may be because of the greater size of the cargo, as mRNAs are exported as large ...
It couples the degradation of an mRNA directly to the proteins produced and is significantly faster and more efficient than previously known mechanisms for mRNA degradation. Crucially, this ...
The COVID-19 pandemic has fundamentally transformed global healthcare systems and vaccine technologies. The accelerated approval and rapid distribution of mRNA vaccines introduced a new paradigm in ...
In many organisms, aging is a clear risk factor for increased rates of chromosome mis-segregation, the main source of aneuploidy. Here, we report that old yeast mother c ...
"Our LNP was able to deliver an mRNA therapeutic that reduced maternal ... as well as understanding the mechanisms of how it gets to the placenta, a question still not fully answered.