The firm’s oral macrocyclic peptides preserved lean muscle mass in mice given the weight-loss drug semaglutide. The company is now looking for a path to bring the peptides into the clinic ...
Dec. 03, 2024 (GLOBE NEWSWIRE) -- Unnatural Products, Inc. (UNP), a biotech developing orally-delivered macrocyclic peptides to address previously undruggable targets, announced today that ...
Macrocyclic compounds can serve as hosts for smaller organic molecules, but precise control over the uptake and release of the guests remains challenging. Now, a host–guest system has been built ...
Helical structures are ubiquitous across biology, from the double-stranded helix of DNA to how heart muscle cells spiral in a band. Inspired by this twisty ladder, researchers from Hiroshima ...
This important study will allow for a better understanding of anthelmintic drug resistance in nematodes, a growing concern for public health. The authors provide a detailed analysis of the role of UBR ...
In a Dutch city famous for the treaty that led to the creation of the European Union, delegates gathered at a conference to discuss recent advances in the chemistry of macrocyclic and ...