Not all genes are active at all times. DNA methylation is one of several epigenetic mechanisms that cells use to control gene expression. This straightforward experiment demonstrated that it was ...

Research published in Nature Ecology & Evolution introduces a novel method for inferring DNA methylation patterns in non-skeletal tissues from ancient specimens, providing new insights into human ...

De novo methylation of CpG islands also occurs in cancer cells, and can result in the transcriptional silencing of growth-regulatory genes. These changes in methylation are early events in ...

The Technion-Israel Institute of Technology will award the Harvey Prize in Science and Technology to Prof. Stephen Baylin, Prof. Peter Jones, and Prof. Andrew Feinberg for their groundbreaking work in ...

Maintaining good cardiovascular health may affect a key process in how cells age, allowing people who are genetically ...

Researchers analyze various aspects of gene regulation, among which are the three-dimensional structure of the genome and DNA methylation, which differ for different cell types and play significant ...

For example, DNA methylation modifies gene expression without altering the nucleotide sequence. A well-studied DNA methylation-based phenomenon is genomic imprinting (ie, genotype-independent ...

Hypertrophic cardiomyopathy (HCM) is a prevalent inherited cardiac disease marked by left ventricular hypertrophy, often due ...

Liver diseases represent a significant global health challenge, encompassing a spectrum of conditions such as hepatitis, fatty liver disease, cirrhosis, and hepatocellular carcinoma. Recent ...

TruDiagnostic envisions a world where healthcare is proactive, not reactive. By integrating EBPs into routine clinical practice, the potential exists to revolutionize population health, reduce ...

During parasitoid wasp infection, activated immune cells of Drosophila melanogaster larvae release adenosine to conserve nutrients for immune response. S-adenosylmethionine (SAM) is a methyl group ...