Recent findings reveal that induced satellite cells can effectively regenerate muscle tissue, outperforming traditional ...

【导读】 针对骨骼肌疾病的实验性细胞疗法收效甚微，主要是因为它们使用定型的肌原祖细胞，而不是真正的肌肉干细胞，即卫星细胞。在这项研究中，团队提出了一种从骨骼肌组织生成体外衍生卫星细胞（idSCs）的方法。

Harvard stem cell biologists have pioneered a groundbreaking 3D organoid culture method for generating large numbers of adult skeletal muscle satellite cells, also known as muscle stem cells, in vitro ...

Furthermore, IFN-β was used to stimulate myoblasts and myotubes, and the relationship between PKR and IFN-β-induced pathogenic molecules was investigated in vitro. Results Bioinformatics analysis ...

Methods: C2C12 myoblasts were proliferated for 24 h and differentiated for 120 h while exposed to hesperetin (5, 20, 50 μM), ellagic acid (0.05, 0.1 μM) or a combination (20 μM hesperetin, 0.05 μM ...

2005). Myofibers are generated by the fusion of terminally postmitotic myocytes, which differentiate from proliferation-competent myoblasts. Due to the linear, one-way succession of proliferating ...

In principle, the mechanisms for setting muscle fiber length might be regulated by the size of the myoblast pool that is available to fuse, the propensity of myoblasts to fuse, the available space ...