8 Tumor of great extension, only focal regression: vacuolization, nuclear piknosis, without nucleoli 6 Tumor of great extension, increased regression in all parts 4 Few tumor nests with marked ...

Primary biliary cirrhosis (PBC) is a chronic, cholestatic liver disease characterized by progressive destruction of intrahepatic bile ducts, resulting in chronic cholestasis, portal inflammation ...

Nucleolar enlargement during aging alters the biophysical properties of nucleoli, which allows entry of DNA repair machinery that is normally excluded. In budding yeast this event triggers ...