The San Francisco 49ers face the Los Angeles Rams at 1:25 p.m. PDT on Sunday, Sept. 22 at SoFi Stadium in Inglewood, CA.

After spending six seasons in red and gold, the former 49ers quarterback will be on the opposing sideline on Sunday in Los Angeles.

Jimmy Garoppolo knows what it feels like as a San Francisco 49er to come to L.A., but now the quarterback is on the other ...

Brock Purdy will lead the San Francisco 49ers on Sunday into their game against the Los Angeles Rams and Mathew Stafford. The 49ers head into this matchup following a 23-17 loss to the Minnesota ...

Add Deebo Samuel to the San Francisco 49ers’ list of injuries woes. The wide receiver will miss “a couple of weeks” due to a ...

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The 49ers woes in Minnesota continued last week when their former quarterback Sam Darnold torched his old squad. The offense ...

A recent proposal from 49ers reporter Matt Barrows of The Athletic suggests a potential trade that could send running back ...

San Francisco 49ers wide receiver Deebo Samuel will be sidelined the next couple of weeks because of a calf strain he endured ...

Analyzing Sunday’s San Francisco 49ers at Los Angeles Rams odds and lines, with expert NFL picks and predictions.

Follow live reaction as the San Francisco 49ers overcame the absence of the injured Christian McCaffrey to comfortably beat ...

San Francisco has dominated the time of possession, controlling the ball for nearly twice as long as New York. Jordan Mason ...