The Highlights Lecture, presented at the closing session of each SNMMI Annual Meeting, was originated and presented for more ...

Despite recent therapeutic breakthroughs, cancer patients continue to face high recurrence and mortality rates due to treatment resistance. Cancer stem cells (CSCs), a subpopulation with self-renewal ...

Objectives Brain dopamine (DA) dysfunction, particularly the dopamine transporters (DAT, main targets of stimulant medications), is implicated in attention deficit/hyperactivity disorder (ADHD). Here ...

Journal of Nuclear Medicine November 2024, jnumed.124.268751; DOI: https://doi.org/10.2967/jnumed.124.268751 ...

Data were collected in 2 separate protocols, 1 to evaluate the dose-range flexibility and 1 to assess test–retest variability. In both protocols, subjects were recruited from the community by the ...

Journal of Nuclear Medicine December 2024, jnumed.124.268068; DOI: https://doi.org/10.2967/jnumed.124.268068 ...

Reagents and antibodies were from Sigma-Aldrich, Roche, Invitrogen, R&D Systems, Santa Cruz Biotech, or Merck-Millipore. [U-14 C]-2-deoxyglucose (9,250 kBq [250 μCi]/mmol) was from New England Nuclear ...

Objectives Acetyl-L-Carnitine (ALC) has been described as playing a neuroprotective effect against a variety of substances. However, the molecular mechanisms underlying its action, particularly ...

Journal of Nuclear Medicine December 2024, jnumed.124.268343; DOI: https://doi.org/10.2967/jnumed.124.268343 ...

Journal of Nuclear Medicine December 2024, jnumed.124.268119; DOI: https://doi.org/10.2967/jnumed.124.268119 ...