with the exception that signage must be posted outside the door of the primary housing room to indicate the presence of human-xenografted animals. The sign is available here. Printing and posting of ...

A research team identified Ru5 as a potent antitumor agent by screening a panel of ruthenium(II) polypyridine complexes ...

This study is led by Prof. Cai-Ping Tan, Prof. Zong-Wan Mao (MOE Key Laboratory of Bioinorganic and Synthetic Chemistry, ...

but triggers apoptosis in cells and xenografted tumours that have already progressed to melanoma 12. The hope is that this, and analogous strategies, may exploit the intrinsic defects in the anti ...

Importantly, IPH45 shows stronger activity than EV, in multiple urothelial carcinoma patient-derived xenografted (PDX) mice models, across Nectin-4 high and Nectin-4 low expression levels.

it was shown to inhibit AKT in human tumours ‘xenografted’ into mice, and to block the tumour growth. A further prototype drug developed by the ICR and Astex team was the pyrrolopyrimidine CCT129254, ...