Aims: To determine the maximum tolerated dose (MTD), safety and anti-tumor activity of afatinib combined with docetaxel in advanced cancer. Patients & methods: The MTD was determined from dose ...
Afatinib (trade name: Giotrif) has been approved since April 2016 for the treatment of adults with locally advanced or metastatic non-small cell lung cancer (NSCLC) of squamous histology who have ...
It serves as another demonstration on batch removal and image contrast conversion of the CytoMAD model. In this experiment, H2170 were treated with 3 drugs of different mechanism of action (MoA) (i.e.
2020; Närhi et al., 2018). HER2-mutant microfluidics-embedded PXDOT models were used to study therapeutic responses to gefitinib, afatinib and neratinib (all at 0.5 μM) over 96 h using dual ...
The Innovation scorecard estimates report is produced by NICE and published by NHS Digital. The report shows the trend in prescribing of NICE recommended first-generation (gefitinib and erlotinib) and ...
Non-small-cell lung cancer (NSCLC) treatment has led to improved efficacy and compliance due to individual tailoring of the therapeutic options and the use of strategies based on both clinical ...
Side effects of prescription and over-the-counter medications are listed on the Medindia website's index page with alphabet A. It's crucial to understand side effects before taking a medication ...