A breakthrough in understanding how a single-cell parasite makes ergosterol (its version of cholesterol) could lead to more ...

A breakthrough in understanding how a single-cell parasite makes ergosterol (its version of cholesterol) could lead to more effective drugs for human leishmaniasis, a parasitic disease that afflicts ...

A breakthrough in understanding how a single-cell parasite makes ergosterol (its version of cholesterol) could lead to more ...

The findings, reported in Nature Communications, also solve a decades-long scientific puzzle that’s prevented drugmakers from successfully using azole antifungal drugs to treat visceral ...

We aimed to estimate the efficacy of different antifungal drugs in the initial treatment of IPA. Methods: We included all available randomized controlled trials (RCTs) evaluating first-line treatments ...

The efficacy and safety of a combination therapy including caspofungin and another antifungal (either AMB or an azole) in a small ... without a major concern about drug-related side effects.