News Medical on MSN8d
Research points the way to lifesaving antiparasitic drugs while unlocking a scientific mystery
A breakthrough in understanding how a single-cell parasite makes ergosterol (its version of cholesterol) could lead to more ...
Discovery of enzyme pathway may lead to lifesaving leishmaniasis treatments
A breakthrough in understanding how a single-cell parasite makes ergosterol (its version of cholesterol) could lead to more ...
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The world's most powerful anti-fungal chemistries cause fungal pathogens to self-destruct
Instead, they found that azole-induced reduction of ergosterol ... The team also tested other clinically relevant anti-fungal drugs that target ergosterol biosynthesis, including terbinafine ...
University of Manchester24y
Deadly mould strains highly likely to acquire resistance to new drugs
Scientists have identified strains of one of the world’s most dangerous fungal pathogens, already resistant to our most ...
Monthly Prescribing Reference9y
Alprazolam Orally Disintegrating Tablets
Alprazolam 0.25mg, 0.5mg. 1mg, 2mg; scored tabs; orange flavor. ≥18yrs: Anxiety: Initially 0.25–0.5mg three times daily. May increase at 3–4 day intervals to 4mg/day in divided doses.
Business Insider India2y
People are getting sick from drug-resistant mold found in their flower beds and compost bins, scientists say
had evolved resistance to two or more azole drugs. Although drug resistance can emerge during treatment in hospital settings, the authors concluded that the fungi in question developed resistance ...
Nature1y
Fighting the rising tide of antifungal resistance: a global challenge
fumigatus, azole-resistance represents a clinically significant challenge. New classes of drugs with new mechanisms of action, like the orotomides, offer a way round the resistance that has ...