Protein glycosylation is a fundamental biological process that regulates various cellular functions, yet its study has been hampered by the complexity and low abundance of glycoproteins.

Chemical tools are small molecules used as probes of a chemical or biological process. Studying the effects of chemical tools on a system can lead to new insight into the molecular target of the ...

Department of Respiratory and Critical Care Medicine, Institute of Respiratory Health, Frontiers Science Center for Disease-Related Molecular Network, State Key Laboratory of Respiratory Health and ...

To address the need for more biofriendly RNA probes, we aimed to develop bioorthogonal chemistries for examining RNA structures. Many bioorthogonal reagents are compact, imparting minimal-to-no ...

Americans Carolyn R. Bertozzi and K. Barry Sharpless, and Danish scientist Morten Meldal were cited for their work on click chemistry and bioorthogonal reactions. “It’s all about snapping ...

Johannes Roth (CRC 1009), Michael Schäfers (CRC 1450), Jan Rossaint (CRU 342) The long road to hybrid parametric imaging in PET/MRI: Methodological challenges and implications for imaging of ...