Yamada et al. evaluated the performance of serum tartrate-resistant acid phosphatase 5b (TRACP5b), a biochemical marker for bone resorption, in comparison with established markers in the ...
an α-emitter (radium-223), the bone resorption-targeting drug denosumab and an immunotherapy (sipuleucel-T). This article describes the molecular mechanisms underlying castration resistance ...
On cessation of lactation, levels of PTHrP and RANKL and the rate of bone resorption decrease (not shown). Babey et al. 3 recently described a mechanism of skeletal recovery (Panel B). Kisspeptin ...
A new study in mice shows how the small GTPase Cdc42 influences bone modeling and remodeling—it modulates both the formation and function of osteoclasts, and is involved in the downstream ...