Yamada et al. evaluated the performance of serum tartrate-resistant acid phosphatase 5b (TRACP5b), a biochemical marker for bone resorption, in comparison with established markers in the ...
Release of the drug from the bone mineral matrix requires bone resorption, and reduction in bone resorption is the primary mode of action of bisphosphonates. The terminal half-life of alendronate ...
A new study in mice shows how the small GTPase Cdc42 influences bone modeling and remodeling—it modulates both the formation and function of osteoclasts, and is involved in the downstream ...