The best explored example of this phenomenon is the CYP2C19 polymorphism. In this table the most frequent alleles are presented that are important for the clinical practice [11,16]. Data on rare ...
In rapid metabolizers of the CYP2C19 isoenzyme, the clearance of omeprazole, lansoprazole and pantoprazole markedly increased compared with that of poor metabolizers, resulting in lower plasma ...
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And in patients with Child-Pugh C, CYP2C19 genotype had no significant effect on voriconazole blood concentrations. Recommendations for presenting dosing programs based on different CYP2C19 genotypes ...
Examples of drugs that increase the activity of these enzymes include: If you take Epidiolex with a drug that increases the activity of the CYP3A4 or CYP2C19 enzymes, Epidiolex may be less effective.