Paraneoplastic cerebellar degeneration (PCD) with anti-Yo antibodies represents a rare immune-mediated paraneoplastic neurological syndrome. Its diagnosis and management remain clinically challenging.

Phenotype can, therefore, be a more reliable means of identification. From a diagnostic viewpoint, categorisation of autosomal recessive ataxias as either resembling a Friedreich's ataxia phenotype or ...

Sex differences were also observed in the study by Wang et al. where men displayed a greater degree of age-related cerebellar atrophy than women. The authors utilized convolutional neural networks to ...

Your brain goes through a “rewiring” process that’s complete around age 25. Here’s why and which stages of your brain mature ...

The PND included encephalomyelitis/sensory neuropathy (five patients), cerebellar degeneration (one), and opsoclonus (one). All anti-amphiphysin I antibodies reacted with the C terminus of amphiphysin ...

Brain atrophy refers to a loss of brain cells, or a loss in the number of connections between brain cells. It can occur as a result of the natural aging process, injury, infection, or certain ...

MRI studies show cerebral and cerebellar atrophy, extensive white mater lesions of the spinal cord, and bilateral T2/FLAIR hyperintensity of the dentate nuclei and surrounding white matter.

Higher levels of societal inequality are linked to reduced brain volume and disrupted connectivity, contributing to increased ...

Researchers from Trinity College Dublin have collaborated with international partners to explore if societal inequality ...

Socio-economic disparities may cause changes in brain structure and connectivity associated with ageing and dementia, ...

Astellas has suffered another major setback with geographic atrophy (GA) treatment Izervay, this time in the US. The company has received a complete response letter (CRL) from the FDA for a ...