In 2024, multiple drugs received complete response letters (CRLs), sometimes unrelated to the safety and efficacy of the drug ...

Can Heart Heal Itself?A research team co-led by a physician-scientist at the University of Arizona College of Medicine – ...

The efficacy of individual treatment approaches with contrasting cholinergic and glutamatergic mechanisms of action prompted investigation of the effects of targeting both systems for the ...

Glucagon-like peptide-1 (GLP-1) receptor agonists have quickly become some of the most ubiquitous drugs in the United States. Though they were originally indicated to treat diabetes, and to assist ...

The use of combination therapy with a cholinomimetic (AChEI) and a glutamatergic (memantine) agent for the treatment of AD is justified by findings from biochemical studies, and preclinical ...

The importance of the brain renin-angiotensin system in cardiovascular function is well accepted. However, not knowing the precise source of renin in the brain has been a limitation toward a complete ...

1Department of Hematology, The First Affiliated Hospital of Xiamen University and Institute of Hematology, School of Medicine, Xiamen University, Xiamen, China. 2Key Laboratory of Xiamen for Diagnosis ...