Although bronchial hyperresponsiveness to cholinergic agents is a main feature of asthma, the role of anticholinergic drugs in chronic asthma management has been largely underestimated.

Drugs acting on the cholinergic system can improve or worsen cognitive abilities, and their effects are particularly pronounced in frail elderly individuals and patients with Alzheimer disease.

The newly approved medicines in 2024 from Massachusetts companies range from a schizophrenia drug to a gene therapy for ...

This article examines the existing scientific applicability of the original cholinergic hypothesis of Alzheimer’s disease by describing ... at postmortem and neurosurgical cerebral biopsy and the ...

In 2024, multiple drugs received complete response letters (CRLs), sometimes unrelated to the safety and efficacy of the drug ...

Consequently, combination therapy currently involves the administration of one cholinergic drug (donepezil, galantamine or rivastigmine) and one glutamatergic drug (memantine). There have been no ...

Discover groundbreaking research on how chronic alcohol use affects cognitive flexibility and brain signaling circuits, ...

For around 70 years, the treatment of schizophrenia has relied almost entirely on drugs that block dopamine receptors, so Cobenfy's action on cholinergic receptors offers a brand new way to treat ...

The company told CBS it will charge around $80 for a 30-day supply of Vuity, a once-daily eyedrop formulation of muscarinic cholinergic ... the condition. The drug may find a market among people ...

Can Heart Heal Itself?A research team co-led by a physician-scientist at the University of Arizona College of Medicine – ...

“All the early work came from here: the cholinergic drugs [the medicines Donepezil, Rivastigmine and Galantamine], used by the NHS to treat symptoms of Alzheimer’s disease came out of work ...