The interplay of mainly depressant and occasionally activating effects of alcohol creates chaos in the brain, leading to ...

Accordingly, although there is presently no “cure” for Alzheimer’s disease, a large number of potential therapeutic interventions have emerged that are designed to correct loss of presynaptic ...

Defects in the cholinergic signaling pathway have been shown to underlie Alzheimer’s disease and its symptoms.

Drugs acting on the cholinergic system can improve or worsen cognitive abilities, and their effects are particularly pronounced in frail elderly individuals and patients with Alzheimer disease.

Although compounds with a combined cholinergic–glutamatergic action have been trialed, none has yet been successful in the later stages of development (Table 4). Consequently, combination ...

Mid-level intoxication with some organophosphates initially produce marked cholinergic symptoms due to muscarinic receptor stimulation. Nicotinic receptor blockage occurs within 1–3 days ...

Cholinergic receptors also play a role in ... and others use this tool to score the severity of schizophrenia symptoms. The clinical trials showed that people taking Cobenfy had a meaningful ...

However, other types of dermatitis and eczema have more specific names, different symptoms, and other features ... other types of dermatitis, including cholinergic urticaria (heat hives) and ...

Their findings, recently published in Science Advances, demonstrate the significant role of cholinergic interneurons (CINs) in this process. Zhenbo Huang, Ph.D., an associate research scientist in ...

The first symptoms of not eating can include fatigue, difficulty concentrating, and nausea, in part due to hypoglycemia (low blood sugar). As time goes on, more severe symptoms like slurred speech, ...

Though symptoms of premenstrual syndrome (PMS) and pregnancy are often similar, there are several key differences and certain symptoms that are unique to each. Premenstrual syndrome (PMS ...