Chromatin is a flexibly joined chain of nucleosomes that exists inside the nucleus of eukaryotic cells and has been described as a 'bead on a string'. Chromatin organization strengthens DNA for ...
You will be redirected to our submission process. Recent years have seen rapid progress in our understanding of the structure and function of eukaryotic chromosomes- the mechanisms by which they are ...
So, this whole idea of chromatin packing and chromatin folding comes into play, of where are the genes in the cell, and how are they regulated that way,” remarked Cosgrove. “Generally, methylation at ...
We show that TPR is required for the activation of innate immune signalling at these early stages of senescence and we link this to the formation of heterochromatin-enriched cytoplasmic chromatin ...
Cancer is a disease driven by progressive genetic and epigenetic aberrations that manifest as global alterations in chromatin packaging and by specific promoter changes that influence the ...
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The researchers used chromatin profiling and high-resolution imaging on stretched chromatin fibers to observe these shifts in detail. "Regardless of the evolutionary forces driving this turnover ...