Translocations generate novel chromosomes, but are often linked to disorders like infertility and cancer. How do these new chromosomes generate problems, and how are they detected? Translocations ...

Translocations, in genetics, happen when chromosomes break and the pieces attach to other chromosomes. This mixing of genetic material has important results. The resultant chromosomes are lacking ...

The transfer between the long arms of chromosomes 9 and 22 is called a reciprocal translocation. In Figure 1, the arrows indicate the translocation breakpoints for each of the involved chromosomes.

Research conducted at the Department of Biology, University of Padova, has identified critical genomic milestones in the ...

Chromosomal translocations occur in leukemias, lymphomas, sarcomas and some epithelial tumors and some generate unique fusion proteins. These translocation products may provide tumor-specific ...

Sometimes though, Wolf-Hirschhorn syndrome is caused when one of the parents has something called a “balanced translocation.” That means two or more of their chromosomes broke and switched ...

The change usually involves the swapping of DNA between chromosomes 22 and 11. This is called chromosomal translocation. When the chromosomal translocation occurs, a piece of chromosome 11 moves ...

All array platforms will detect copy number variations including deletions, duplications, unbalanced translocations, some marker chromosomes and aneuploidy. SNP arrays have the added advantage of ...

The first gene in the class, subsequently named the LIM Domain Only genes (LMO), was found as a transcribed region on human chromosome 11 band p15 near to a T cell acute leukaemia chromosomal ...