【导读】环状RNA（circRNA）是一种具有共价闭合单链环状结构的调节性RNA。有证据表明，circRNA在多种癌症的进展和发展中发挥着重要作用。然而，circRNA对结直肠癌（CRC）自噬介导的进展的影响尚不明确。

为了探究circPIAS1是否可以通过抑制STAT1磷酸化过程来减轻免疫介导的铁死亡，研究人员对肿瘤组织进行了IHC染色分析。ASO-circPIAS1与PD-1抑制剂的联合治疗导致P-STAT1水平显著升高，而GPX4水平则呈相反趋势。此外，研究人 ...

“非常期待这款工具能得到深入应用，目前已经有好几个实验室找我们要这个工具。”湘湖实验室李果研究员表示。图 | 李果（来源：李果）日前，他和合作者发现了极小型 Cas13j 蛋白，并实现了高效的体内 RNA ...

RNA vaccines are composed of the nucleic acid RNA, which encode antigen genes of an infectious agent. When administered to host cells, the RNA is translated into protein antigens that elicit ...

A Rare Case of Falsely Elevated High-Sensitivity Cardiac Troponin T due to Antibody Interference and a Literature Review.

Houston Methodist researchers will be part of a national consortium funded by an up to $49 million award from the U.S. Government's Advanced Research Projects Agency for Health (ARPA-H) to develop ...