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3 天
免疫逃逸新机制!中国药科大学合作发文:改善肿瘤治疗效果的新策略
为了探究circPIAS1是否可以通过抑制STAT1磷酸化过程来减轻免疫介导的铁死亡,研究人员对肿瘤组织进行了IHC染色分析。ASO-circPIAS1与PD-1抑制剂的联合治疗导致P-STAT1水平显著升高,而GPX4水平则呈相反趋势。此外,研究人 ...
5 天
激活自噬并诱导化疗耐药!郑州大学发文:结直肠癌进展新见解
【导读】环状RNA(circRNA)是一种具有共价闭合单链环状结构的调节性RNA。有证据表明,circRNA在多种癌症的进展和发展中发挥着重要作用。然而,circRNA对结直肠癌(CRC)自噬介导的进展的影响尚不明确。
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