Claudin-1 (CLDN1) is a protein usually found nestled between epithelial cells — which cover internal and external body surfaces — helping to bind them. “It works like a zipper to keep two ...

Claudin is a protein family that contains at least 27 members and it was first identified by Furuse in 1998. It is a four-pass transmembrane protein that has been expressed at the epithelial ...

Other companies developing claudin 18.2-targeted therapies include Innovent, which started dosing patients with its IBI343 antibody in a phase 1 trial involving patients with various solid tumours ...