We have previously reported that cultures of C. albicans activated the amebocyte lysate clotting cascade of the Japanese horseshoe crab Tachypleus tridentatus. In order to isolate the active agent ...

Coagulation markers: Higher concentrations of microplastics in the blood are linked to higher levels of coagulation markers.

Its mechanism of action is depicted in Figure 1. Heparin has a multitude of effects on the clotting cascade; however, the primary sites of action are the inhibition of factor II, also called ...

The top panel, designed with BioRender.com, illustrates the process of clot formation and lysis, beginning with platelet aggregation and activation of the coagulation cascade, followed by the ...

See Figure 1 for a depiction of normal hemostasis. The activation of the coagulation cascade yields thrombin that converts fibrinogen to fibrin; the stable fibrin clot being the final product of ...