Learn about CYP suppression, immunomodulators, and how to identify DDR risks using studies on CYP suppression.

Hot Spot. GWAS of tau PET scans found a single locus where SNPs (circles) were associated with higher tangle loads. The strongest signal came from SNP rs2113389 (gray diamond). [Courtesy of Nho et al.

Proteolytic enzymes (proteases) have several potential uses, such as aiding digestion, supporting immunity, improving healing, and more. Your body uses these enzymes to break down protein. While your ...

Co-administration of a cytochrome P450 (CYP) 2C8 enzyme inhibitor (e.g., gemfibrozil) may increase exposure (both C max and AUC) to treprostinil. Co-administration of a CYP2C8 enzyme inducer (e.g ...

Lactase is a digestive enzyme involved in the breakdown of lactose, a sugar found in milk and other dairy products. People with lactose intolerance cannot produce enough lactase on their own. In the ...

They used three different engineered P450 enzymes to carry out selective C–H oxidations and epoxidations. Fasan says those enzymatic transformations provided a “springboard” to additional ...