Ruxolitinib phosphate is under clinical development by Incyte and currently in Phase III for Coronavirus Disease 2019 (COVID-19) Associated Cytokine Release Syndrome.

1Genentech Inc., South San Francisco, California.

Itacitinib adipate is under clinical development by Incyte and currently in Phase II for Myelodysplastic Syndrome.

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Cytokine release syndrome (CRS) developed in all patients, including grade 3/4 events in nearly half. "Bicistronic CD19/CD22-targeted CAR T-cell therapy is a safe and effective regimen which ...

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The usual reason for such sudden fatalities is given as massive cardiac arrests or fatal brain strokes. However, everybody ...

The study showed that all doses of POLB 001 significantly reduced clinically observed Cytokine Release Syndrome (CRS) scores, reinforcing its potential in preventing and treating cancer ...

Using real-world data, Song found that patients treated with CAR T-cell therapies had improved overall survival compared with ...

MONDAY, Dec. 9, 2024 (HealthDay News) -- For patients with haploidentical hematopoietic cell transplantation (haplo-HCT), the addition of itacitinib to standard graft versus host disease (GvHD) ...

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The following is a summary of “REmoval of cytokines during CArdiac surgery (RECCAS): a randomised controlled trial,” published in the December 2024 issue of Critical Care by Hohn et al.