Alterations in cytokine expression associated with inflammation have long been observed in individuals with immune-mediated disease. Clinical trials carried out almost a decade ago were the first ...
Figure 1. Cytokines involved in acute and chronic inflammatory responses (DOI:10.2741/a171). Image Credit: Sino Biological Inc. Disturbance in levels of the key pro-inflammatory cytokines ...
They could also be the reason why younger people are less affected, as their immune systems are less developed and so produce lower levels of inflammation-driving cytokines. In 2006, six healthy ...
T helper 17 (Th17) cells generate the pro-inflammatory cytokine interleukin-17 (IL17/IL17A). IL17 has been a target for a variety of therapeutic monoclonal antibodies and inhibitors to treat ...