Introduction: Dengue viruses (DENVs), the causative agents of dengue hemorrhagic fever and dengue shock syndrome, undergo genetic mutations that result in new strains and lead to ongoing global ...
No large RNA structure database exists that correlates sequence with 3D topology. Successful protein-centric methods like AlphaFold remain unavailable for RNA, creating a critical gap in ...
The NS5-B quadruplex sequence, which is located in the genome region encoding the methyltransferase domain of the viral polymerase, was selected for this study based on previous biophysical ...
Dengue is a miserable illness caused by infection with any of the four dengue viruses (dengue-1, -2, -3 and -4). Infections have increased dramatically over the past two years while, at the same ...
In fact, a new study by the Tuschl laboratory introduces a proof-of-concept for a novel class of antivirals that would target a type of enzyme essential not just to SARS, but also many RNA viruses, ...
After consulting with doctors in the Boston area, he learned that he had dengue fever. The diagnosis shocked Korb, my 47-year-old cousin, who frequently travels to tropical destinations.
Dengue fever is a common tropical infection. This acute febrile illness can be a deadly infection in cases of severe manifestation, causing dengue hemorrhagic shock. In this brief article, I will ...
This escalating risk of a new RNA virus pandemic highlights the urgent need to implement One Health strategies. However, the centralised virus detection systems currently in use fall short of meeting ...
Introduction: Dengue Fever continues to pose a global threat due to the widespread distribution ... Visualization of the resultant energy minimized protein structure and the removal of surrounding ...