ALTHOUGH the role of pyridoxal phosphate as a coenzyme of amino-acid decarboxylases is generally recognized, attempts to demonstrate its participation in the enzymic decarboxylation of histidine ...

The reaction is therefore thought to be enzymic. The flavin cannot be detected in unincubated homogenates which have been concentrated many times by Crammer's 1 method for extracting flavins.

Aggregation of Cu–Zn superoxide dismutase (SOD1) is implicated in the motor neuron disease, amyotrophic lateral sclerosis (ALS). Although more than 140 disease mutations of SOD1 are available, their ...