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15 天
4款创新药乳腺癌临床数据最新公布!来自康方生物、贝达药业等
根据贝达药业此前新闻稿,基于该3期研究结果,泰贝西利胶囊的上市申请已经获中国NMPA受理。 ESG401是诗健生物首个临床阶段管线,为一种新型TROP2靶向ADC,通过可切割的稳定连接子将拓扑异构酶I抑制剂SN-38与人源化TROP2 IgG1单克隆抗体偶联,药物抗体偶联比(DAR ...
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20 天
2024 ESMO预告!哪些国产ADC值得期待?
ESG401是诗健生物重点开发的一款Trop-2 ADC,是诗健生物首个进入临床阶段的ADC产品。其采用了创新型稳定可降解联接子,显著降低了脱靶毒性。已有的临床研究数据显示,ESG401的脱靶毒性和在靶毒性的发生率低且程度轻,具有明显的安全性优势。 在研发进展上 ...
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