编者按:随着基因检测技术的飞速发展,原发不明肿瘤(cancer of unknown primary,CUP)患者的治疗策略正经历着革命性变革。在2024年ESMO大会期间,世界原发不明肿瘤联盟(the World CUP Alliance)在ESMO大会上专门召开了“精准肿瘤学的获取和认知圆桌会议”(Roundtable on access & awareness of precision on ...
A critical review of the limitations posed by current preclinical animal models of Alzheimer's disease and of the oversimplistic assumptions proposed by the amyloid cascade hypothesis (ACH).
In this study, we investigated the neuronal activity of the dentate gyrus (DG) with electrophysiological and optical imaging tools during sleep-wake cycles. We found that the activity of major ...