Thus, in the current study, PDT with the photosensitizer hypericin (Hyp), formulated in mixed 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC)/biotinylated-pluronic F127 (F127–B) liposomes, in ...
Ferroptosis was first identified in RAS-mutant cancer cells exposed to erastin and related compounds, which inhibit the cystine/glutamate antiporter (system Xc-) and impair GSH synthesis.
Our perspective about glucose toxicity as it pertains to the pancreatic ß-cell is that the characteristic decreases in insulin synthesis and secretion are caused by decreased insulin gene expression.
BSO: Buthionine sulfoximine; DMARD: Disease-modifying antirheumatic drug; H 2 S: Hydrogen sulfide; GSH: Glutathione; LUTS: Lower urinary tract syndromes; PDE5: Type 5 ...
Since cysteine serves as a substrate for glutathione synthesis and inhibits ferroptosis, cysteine depletion could restore chemosensitivity in breast cancer cells. Moreover, reducing cystine and GSH ...
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A C-like hardware description language (HDL) adding high level synthesis(HLS)-like automatic pipelining as a language construct/compiler feature.