Co-release of the functionally opposing fast neurotransmitters, glutamate and GABA, from distinct synaptic vesicles within the same supramammillary synaptic terminal modulates dentate granule cell ...

Neuroprotection by sigma agonists is accomplished by a variety of mechanisms like inhibition of presynaptic glutamate release and attenuation of postsynaptic glutamate-evoked Ca2+ influx.

Adenosine A1 receptors are expressed presynaptically where they compete with A2A receptors through receptor-receptor interactions to inhibit glutamate release. Postsynaptically, A1 receptors are ...

Similarly, mimicking the effects of high-frequency stimulation by increasing intracellular Ca 2+ levels with calcimycin caused CAPS DKO neurons to spontaneously release glutamate to the same ...

A new approach to treat rosacea and other inflammatory skin conditions could be on the horizon, according to a University of ...

A new approach to treat rosacea and other inflammatory skin conditions could be on the horizon, according to a University of ...

[31] Glutamine is formed and cycles from astrocytes to presynaptic neurons, where glutamate is formed. After release into the synaptic cleft, reuptake of glutamate occurs in astrocytes. A profound ...

THURSDAY, Dec. 12, 2024 (HealthDay News) -- It's still early science -- studies in mice and in human cells -- but researchers are on the trail of an effective new treatment for inflammatory skin ...

Ltd., today announced that they have entered into a license agreement to develop, manufacture and commercialize Newron’s ...