One such pathway, the hypoxic response pathway, is activated by reduced local oxygen concentrations at the tumor site. Hypoxia-driven gene and protein changes enhance epithelial-to-mesenchymal ...

Ace investor Shankar Sharma, a.k.a. Le Grand Fromage, unveils the 'SSIPHO' method - blending breakthrough medical science with cutting-edge investment strategy.

At this point, descent to lower altitude or treatment in a (portable) pressure chamber and administration of oxygen are critical to prevent hypoxia and life-threatening high-altitude hypoxic brain ...

Recently, exposures to altitude/hypoxia have been suggested to provide an alternative strategy. In particular, anecdotal and scientific observations of weight loss and appetite reduction at high ...

Third, the development of new hypoxic devices (eg, mobile inflatable hypoxic marquees) and methods (repeated sprints in hypoxia). This increased interest was translated by the organisation of ...

“However, it has been unknown, under hypoxia, whether and how HIF1α regulates IFN-γ induction and glycolysis in T cells.” The UAB researchers found that HIF1α-glycolysis is indispensable for IFN-γ ...

At this point, descent to lower altitude or treatment in a portable pressure chamber and administration of oxygen are critical to prevent hypoxia and life-threatening high-altitude hypoxic brain ...

Immune checkpoint blockades, or ICBs, have revolutionized treatment for various advanced cancers. However, their ...

These studies in fetoplacental vessels showed that acute hypoxia-induced vasoconstriction of fetoplacental arteries reduces placental perfusion. However, capillary network expansion in the chronically ...