The type 1 IGF receptor (IGF-IR) is activated by two ligands, IGF-1 and IGF-2, and by insulin at supraphysiological concentrations. It plays a significant role in the growth of normal and abnormal ...
A list of suggestions for customizing IGF-IR targeting is provided in the Executive summary. One has to seriously consider the hypothesis that cancer cells can acquire the ability of using one ...
With potential to have lonigutamab as a possible best-in-class anti-IGF-1R drug for TED, plus moving rapidly into phase 3 clinical testing, I believe that investors could benefit with any ...