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抗癌生存:从PFS到OS的接力赛,为什么交接棒出了问题?
评估指标:评估癌症治疗效果的关键指标为PFS和OS,OS是最可靠指标,但获取其数据较难,PFS在临床试验中重要,FDA和EMA均认可PFS。 临床试验情况:部分临床试验中PFS和OS数据可能不一致,一些药物PFS数据好但OS数据未体现优势。 影响OS的因素:临床中后续治疗组 ...
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