BARCELONA, Spain — In a groundbreaking study that could reshape our understanding of cancer, scientists have uncovered a treasure trove of potential new targets for cancer treatment. This discovery ...

2 [Alt text] From left to right, the figure outlines key elements of posttranscriptional pre-mRNA splicing: an RNA transcript (pre-mRNA) displaying introns and exons, and six common splicing ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The evolving genetic landscape of inherited ...

Oct. 3: Departmental Seminar with Dr. Sandra L. McLellan and Dr. Lynde B. Uihlein Oct. 10: Departmental Seminar with Dr. Sudeep Sarkar Oct. 17: Departmental Seminar ...

Cells use splicing to cut out unnecessary parts of the draft (introns) and stick together the important bits of information (exons). Cancer cells include or exclude specific exons ... “This could be ...

Researchers at the Centre for Genomic Regulation (CRG) have identified 813 possible cancer driver genes, significantly ...

Cells use splicing to cut out unnecessary parts of the draft (introns) and stick together the important bits of information (exons ... a patient's cancer biology and help oncologists determine ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. DNA i-motif structures are formed in the ...

Notably, modulation of pivotal molecular pathways, including the PI3K/AKT/mTOR, Wnt/β-catenin, JAK/STAT, and MAPK pathways, underscores their significance in CC biology. Moreover, their involvement in ...