This manuscript provides valuable information about the genesis of CPSF6 condensates due to HIV-1 infection. However, the evidence is incomplete as it is missing more functional assays. Furthermore, ...

Additionally, the antibody proved “consistent across subgroups” and appeared well tolerated in both IBD conditions with no safety signals identified, according to the partners. Overall rates ...

This helps support our journalism. Learn more. Please also consider subscribing to WIRED Normally, antibodies are protective proteins produced by our immune systems to fight bacteria or viruses.

developed a diagnostic luciferase assay using all recombinant reagents in which streptavidin-coated ... Following immunization of transgenic mice producing heavy chain-only antibodies, Du et al.

The incorporation of split luciferase significantly improves the operability and quantifiability of ... Additionally, expensive reagents such as labelled antibodies are not required, greatly reducing ...

This includes HSV-1, the type most commonly linked to cold sores, and HSV-2, the type mainly associated with genital herpes. The test doesn't detect the virus itself but instead detects ...

A newly developed luciferase-based reporter can detect problems in protein translocation and disulfide bond formation in the endoplasmic reticulum (ER), as reported by researchers at Science Tokyo.

Sjögren’s antibodies include anti-SS-A (also called anti-Ro) and anti-SS-B (also called anti-La). These antibody levels can be measured in the blood. Anti-SS-A and anti-SS-B are considered ...

In addition, use of an anti-TGF-β1 neutralizing antibody to block TGF-β/Smad3 signaling protects mice from obesity ... was used to measure the protein level of cystatin c in serum according to the ...