Chemical changes to histones, the proteins that help to pack and organize DNA inside cells, play a key role in determining ...

The discovery of histone lysine demethylases has provided the opportunity for a detailed exploration of the regulation of histone-methylation dynamics. Although the focus of the past few years has ...

The sequencing of the human genome at the turn of the 21st century was heralded as a monumental scientific achievement ...

Substrate-Differentiated Transition States of SET7/9-Catalyzed Lysine Methylation. J Am Chem Soc. 2019 May 22;141(20):8064-8067. Chen S, Wiewiora RP, Meng F, Babault N, Ma A, Yu W, Qian K, Hu H, Zou H ...

The Luo Lab is interested in developing and leveraging novel approaches at the interface of chemistry and biology to annotate functional roles of epigenetic modulators. Epigenetic regulation is ...

Among the available options, lysine clonixinate (LC) and naproxen sodium (NS) have proved effective in migraine. The aim of this study was to compare the efficacy and tolerability of oral ...

In fact, biological outcomes are often due to physical interactions between proteins that are so highly selective that seemingly minor chemical modifications (i.e. methylation, acetylation or ...

Mar. 28, 2024 — A research consortium provides evidence that social behavior and social status are reflected at the molecular level of gene activation (epigenome) in ... New Study Reveals ...

Please Contact Dr. Guiliang Tang. Dr. Tang conducted his graduate research on the catabolic pathway of the essential amino acid lysine in the laboratory of Dr. Gad Galili at the Weizmann Institute of ...

I think that's quite striking, in that the more DDE you're exposed to, the higher the chromatin, or DNA methylation defects are in the sperm," said Ariane Lismer, Ph.D., the study's lead author, who ...