Vital research findings pointing to improved treatment for children with brain tumours have been revealed in two major ...

Researchers have identified a critical group of medulloblastoma, a form of brain cancer in children, which is near incurable ...

Vital research findings pointing to improved treatment for children with Group 3 medulloblastoma brain tumors have been ...

A Newcastle team have discovered a "new approach" which could finally lead the way in treating some children who have ...

Researchers have identified a critical group of medulloblastoma, a form of brain cancer in children, which is near incurable ...

Northwestern Medicine scientists have discovered a new mechanism that controls a specialized group of T-cells, known as ...

Additionally, DNp73 promoted immune evasion of MM cells by upregulating MYC target genes CD47 and PD-L1. Blockade of the CD47/SIRPα and PD-1/PD-L1 signaling pathways by the SIRPα-Fc fusion protein ...

By tracking the changes in prostate cancer cells over time, researchers at the Johns Hopkins Kimmel Cancer Center have found that activation of the MYC gene -; a well-known cancer-causing gene -; sets ...

The work demonstrates that initial MYC activation attracts immune cells to the tumor but later helps hide the tumor from immune cells. This discovery is the first step toward identifying potential ...

“This is a very powerful oncogenic pathway set off by MYC activation,” says Srinivasan Yegnasubramanian, M.D., Ph.D., professor of oncology, pathology, and radiation oncology and molecular ...

saying it is possible to secure the border and create an earned pathway to citizenship. She also took aim at Mr. Trump for expressing interest in a deportation operation of immigrants living in ...

However, at pH 6.6, IL-2R signaling was only modestly impacted, and the MAPK/ERK pathway not at all. In contrast, at pH 6.6 we observed that both mTORC1 activation/signaling (as evaluated by ...