This study provides important insights into the regulation of a retained intron in the mRNA coding for OGT, a process known to be regulated by the O-GlcNAc cycling system, and highlights the ...

In this manuscript, Yao et al. present solid evidence to show that MnMYL3 may serve as a receptor for NNV via macropinocytosis. This manuscript is valuable for understanding the molecular mechanisms ...

Protein has become a major focus in the American diet, and for good reason. Research shows that protein is essential for maintaining a healthy immune system, supporting weight management, and ...

Thirteen proteins linked to brain aging in humans are identified in a Nature Aging paper. Changes in the concentrations of these blood proteins may peak at 57, 70, and 78 years old in humans ...

"ProteinTok" is everywhere. From Protein Diet Coke to high-protein desserts, it feels like everyone on the internet is talking about one thing: More. Protein. While plenty talk about protein ...

MRT-2359. That program is MRT-2359, an oral MGD designed to target translation termination factor protein GSPT1 for the treatment of MYC oncogene-driven tumors, including metastatic non-small cell ...

Bored with your current protein supplements and want to try out other protein powders? We've got you covered. Protein powders are a great way to include protein into your diet, especially if you ...

Known as Myc, it was one of the first so-called oncogenes ever discovered. It’s mutated or dysregulated in perhaps 70% of all cancers. The challenge is that the protein it creates is ...

That's because mis-regulation of Myc proteins is a hallmark of cancer and N-Myc plays a key role in childhood brain cancers. "Because Aurora-A stabilizes N-Myc against degradation, inhibiting the ...

In addition to being an oncogene, MYC is also one of the four Yamanaka factors, which are four protein transcription factors that can revert highly specified cells (such as a skin cell ...

1 Department of Clinical Laboratory, Yiyang Central Hospital, Yiyang, Hunan, China 2 Department of Emergency Medicine and Laboratory of Emergency Medicine, West China Hospital, West China School of ...

Summary: Ketone bodies, known for their role in energy metabolism during fasting, have been shown to directly interact with damaged proteins in the brain, aiding their clearance through autophagy.